| 1 | Los Angeles Rams (de Tennessee) | Jared Goff, QB, California |
| 2 | Philadelphia Eagles (de Cleveland) | Carson Wentz, QB, North Dakota State |
| 3 | San Diego Chargers | Laremy Tunsil, OT, Mississippi |
| 4 | Dallas Cowboys | Jalen Ramsey, DB, Florida State |
| 5 | Jacksonville Jaguars | Joey Bosa, DE, Ohio State |
| 6 | Baltimore Ravens | DeForest Buckner, DE, Oregon |
| 7 | San Francisco 49ers | Myles Jack, LB, UCLA |
| 8 | Cleveland Browns (de Miami vía Philadelphia) | Ronnie Stanley, OT, Notre Dame |
| 9 | Tampa Bay Buccaneers | Vernon Hargreaves III, CB, Florida |
| 10 | New York Giants | Ezekiel Elliott, RB, Ohio State |
| 11 | Chicago Bears | Shaq Lawson, DE, Clemson |
| 12 | New Orleans Saints | A'Shawn Robinson, DT, Alabama |
| 13 | Miami Dolphins (de Philadelphia) | Eli Apple, CB, Ohio State |
| 14 | Oakland Raiders | Sheldon Rankins, DT, Louisville |
| 15 | Tennessee Titans (de Los Angeles) | Jack Conklin, OT, Michigan State |
| 16 | Detroit Lions | Leonard Floyd, LB, Georgia |
| 17 | Atlanta Falcons | Laquon Treadwell, WR, Mississippi |
| 18 | Indianapolis Colts | Taylor Decker, OT, Ohio State |
| 19 | Buffalo Bills | Robert Nkemdiche, DT, Mississippi |
| 20 | New York Jets | Reggie Ragland, LB, Alabama |
| 21 | Washington Redskins | Jarran Reed, DT, Alabama |
| 22 | Houston Texans | Derrick Henry, RB, Alabama |
| 23 | Minnesota Vikings | Josh Doctson, WR, Texas Christian |
| 24 | Cincinnati Bengals | Will Fuller, WR, Notre Dame |
| 25 | Pittsburgh Steelers | William Jackson III, CB, Houston |
| 26 | Seattle Seahawks | Darron Lee, LB, Ohio State |
| 27 | Green Bay Packers | Andrew Billings, DT, Baylor |
| 28 | Kansas City Chiefs | Kevin Dodd, DE, Clemson |
| 29 | Arizona Cardinals | Mackensie Alexander, CB, Clemson |
| 30 | Carolina Panthers | Corey Coleman, WR, Baylor |
| 31 | Denver Broncos | Paxton Lynch, QB, Memphis |
