Antonio Candreva struck the winner 12 minutes from time at the Stadio Olimpico as Lazio came from behind to beat Palermo on Sunday and maintain their push for Champions League football next season.
Lazio captain Stefano Mauri cancelled out Paulo Dybala's opener in the 33rd minute before Candreva put the Romans ahead in the 78th minute to hand the Biancoceleste their second straight triumph.
Palermo ended the game with just 10 men after Edgar Barreto was sent off for a double booking with seconds remaining.
Lazio are now fourth in Serie A and trailed third-place Napoli, who host Sassuolo on Monday, by two points.
Palermo, who beat Napoli 3-1 in the previous round, still have not won away from home since November 2.
They dropped to ninth after Sunday's defeat.
The hosts went into the game bolstered by the return of goalkeeper Federico Marchetti and midfield pair Lorik Cana and Stefano Mauri from suspension.
Palermo started well and could have taken an early lead when Edgar Barreto fed Dybala in the box but the Argentinian's 15-yard attempt was kept out by Marchetti.
Mauri almost put the home side ahead in the 20th minute.
The Italy international got behind Stefan de Vrij's pass and unleashed a left-footed shot towards the near post but Palermo goalkeeper Stefano Sorrentino was equal to the task.
Palermo went in front in the 26th minute against the run of play.
Robin Quaison set up an unmarked Dybala in the box and he struck the ball towards the near post and out of Marchetti's reach.
Lazio hit back seven minutes later.
Sorrentino could do nothing as Danilo Cataldi's cross found Mauri and he fired the ball into the roof of the net from five yards.
The visitors had a good chance to regain the lead before the interval but Marchetti pulled off a great reaction save to deny Achraf Lazaar from close range.
After the re-start and in the 48th minute, Palermo's Franco Vazquez's stinging drive from 30 yards forced Marchetti to palm the ball over the bar.
Lazio showed more intent and almost took the lead in 65th minute but Vazquez made a goal-line clearance from Mauri's goal-bound header with Sorrentino already beaten.
The Romans wasted a good chance in the 72nd minute.
Sorrentino kept out Antonio Candreva's right-footed volley but Miroslav Klose struck the rebound wide.
Lazio's perseverance paid off moments later.
Candreva got past his marker and drilled a right-footed shot towards the top right corner of goal to beat Sorrentino.
Palermo could not find the equaliser and with seconds remaining, Barreto was handed his marching orders after being booked for the second time after a late challenge on Keita.
ends