| Pitcheo | ||||||||||||||||
| Rank | JUGADOR | EQUIPO | JJ | JI | EL | H | D | CL | BB | P | G | P | SALV | HLD | BLSV | EFE |
| 1 | Andy Pettitte | NYY | 5 | 5 | 30.2 | 26 | 12 | 12 | 11 | 25 | 4 | 0 | 0 | 0 | 0 | 3.52 |
| 2 | CC Sabathia | NYY | 5 | 5 | 36.1 | 28 | 9 | 8 | 9 | 32 | 3 | 1 | 0 | 0 | 0 | 1.98 |
| 3 | David Robertson | NYY | 5 | 0 | 5.1 | 4 | 0 | 0 | 3 | 3 | 2 | 0 | 0 | 0 | 0 | 0.00 |
| 4 | Darren Oliver | LAA | 8 | 0 | 8.2 | 7 | 3 | 3 | 4 | 8 | 1 | 0 | 0 | 1 | 1 | 3.12 |
| A.J. Burnett | NYY | 5 | 5 | 27.1 | 22 | 16 | 16 | 16 | 24 | 1 | 1 | 0 | 0 | 0 | 5.27 | |
| John Lackey | LAA | 3 | 3 | 19.2 | 19 | 7 | 5 | 7 | 14 | 1 | 1 | 0 | 0 | 0 | 2.29 | |
| Ervin Santana | LAA | 4 | 0 | 5.2 | 5 | 3 | 1 | 4 | 5 | 1 | 1 | 0 | 0 | 0 | 1.59 | |
| Jered Weaver | LAA | 4 | 2 | 13.2 | 7 | 4 | 4 | 6 | 14 | 1 | 0 | 0 | 1 | 0 | 2.63 | |
| Joba Chamberlain | NYY | 10 | 0 | 6.1 | 9 | 2 | 2 | 1 | 7 | 1 | 0 | 0 | 3 | 1 | 2.84 | |
| Kevin Jepsen | LAA | 5 | 0 | 5.0 | 8 | 2 | 2 | 2 | 3 | 1 | 0 | 0 | 1 | 0 | 3.60 | |
| Rank | JUGADOR | EQUIPO | JJ | JI | EL | H | D | CL | BB | P | G | P | SALV | HLD | BLSV | EFE |
| 11 | Ron Mahay | MIN | 3 | 0 | 1.2 | 0 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 5.40 |
| Mariano Rivera | NYY | 12 | 0 | 16.0 | 10 | 1 | 1 | 5 | 14 | 0 | 0 | 5 | 0 | 0 | 0.56 | |
| Billy Wagner | BOS | 2 | 0 | 1.0 | 2 | 2 | 2 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 18.00 | |
| Carl Pavano | MIN | 1 | 1 | 7.0 | 5 | 2 | 2 | 0 | 9 | 0 | 1 | 0 | 0 | 0 | 2.57 | |
| Joe Nathan | MIN | 2 | 0 | 2.0 | 5 | 2 | 2 | 1 | 2 | 0 | 0 | 0 | 0 | 1 | 9.00 | |
| Damaso Marte | NYY | 8 | 0 | 4.0 | 2 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 3 | 0 | 0.00 | |
| Josh Beckett | BOS | 1 | 1 | 6.2 | 5 | 4 | 4 | 1 | 3 | 0 | 1 | 0 | 0 | 0 | 5.40 | |
| Jon Rauch | MIN | 3 | 0 | 1.1 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 6.75 | |
| Brian Fuentes | LAA | 5 | 0 | 4.2 | 1 | 1 | 1 | 4 | 3 | 0 | 0 | 3 | 0 | 1 | 1.93 | |
| Chad Gaudin | NYY | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | |
| Rank | JUGADOR | EQUIPO | JJ | JI | EL | H | D | CL | BB | P | G | P | SALV | HLD | BLSV | EFE |
| Scott Kazmir | LAA | 3 | 2 | 10.2 | 11 | 10 | 9 | 8 | 4 | 0 | 1 | 0 | 0 | 0 | 7.59 | |
| Brian Bruney | NYY | 1 | 0 | 0.1 | 3 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 54.00 | |
| Matt Guerrier | MIN | 2 | 0 | 2.0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 0.00 | |
| Francisco Liriano | MIN | 1 | 0 | 2.0 | 1 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 4.50 | |
| Jason Bulger | LAA | 4 | 0 | 3.1 | 1 | 1 | 1 | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 2.70 | |
| Jonathan Papelbon | BOS | 2 | 0 | 2.0 | 4 | 3 | 3 | 2 | 1 | 0 | 1 | 0 | 0 | 1 | 13.50 | |
| Joe Saunders | LAA | 2 | 2 | 10.1 | 13 | 5 | 5 | 6 | 5 | 0 | 1 | 0 | 0 | 0 | 4.35 | |
| Takashi Saito | BOS | 1 | 0 | 1.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | |
| Ramon Ramirez | BOS | 1 | 0 | 0.0 | 1 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | |
| Jon Lester | BOS | 1 | 1 | 6.0 | 4 | 3 | 3 | 4 | 5 | 0 | 1 | 0 | 0 | 0 | 4.50 | |
| Rank | JUGADOR | EQUIPO | JJ | JI | EL | H | D | CL | BB | P | G | P | SALV | HLD | BLSV | EFE |
| Hideki Okajima | BOS | 1 | 0 | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | |
| Phil Hughes | NYY | 9 | 0 | 6.1 | 11 | 6 | 6 | 4 | 7 | 0 | 1 | 0 | 2 | 1 | 8.53 | |
| Clay Buchholz | BOS | 1 | 1 | 5.0 | 6 | 2 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 3.60 | |
| Nick Blackburn | MIN | 1 | 1 | 5.2 | 3 | 1 | 1 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 1.59 | |
| Brian Duensing | MIN | 1 | 1 | 4.2 | 7 | 5 | 5 | 1 | 3 | 0 | 1 | 0 | 0 | 0 | 9.64 | |
| Matt Palmer | LAA | 2 | 0 | 2.2 | 5 | 4 | 4 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 13.50 | |
| Alfredo Aceves | NYY | 4 | 0 | 4.1 | 5 | 2 | 2 | 3 | 2 | 0 | 1 | 0 | 0 | 0 | 4.15 | |
| Phil Coke | NYY | 6 | 0 | 2.2 | 4 | 2 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 6.75 | |
| Jose Mijares | MIN | 2 | 0 | 0.2 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 13.50 | |
| Daniel Bard | BOS | 2 | 0 | 3.0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 0.00 | |
Data provided by Elias Sports Bureau