A quick-fire double from Kevin Gameiro helped Sevilla beat Malaga 2-1 in a fierce Andalusian derby which saw both teams finish the game with 10 men.
The Frenchman struck twice in the space of 99 seconds at the end of the first half to put Sevilla in charge and although Charles reduced the deficit after 71 minutes, Malaga could not find an equaliser.
The visitors were handed a late advantage when Vicente Iborra was sent off for two bookings, but Arthur Boka followed him down the tunnel just a few minutes later, and their eight-game unbeaten run in the league was brought to an end.
Sevilla, meanwhile, were left to celebrate a ninth successive home victory as Unai Emery's men continued their pursuit of a top-four place.
Sevilla went into the game on a high after thumping local rivals Real Betis 4-0 in midweek to qualify for the quarter-finals of the Copa del Rey.
And after a lively and evenly matched start to another Andulusian derby they took the lead after 39 minutes when Adil Rami sent in a free-kick towards Gameiro, who cleverly chipped the ball over Carlos Kameni.
Just moments later the Frenchman tapped in a pass from Vitolo to complete a counter-attack and hit his 11th league goal of the season.
Malaga improved in the second half while Sevilla wilted, and Charles pulled a goal back by turning the ball in at the far post.
Substitute Iborra was then sent off 20 minutes after coming on to seemingly give Malaga a lifeline, earning a second booking for an ugly tackle, but the numbers were evened up when Boka picked up two yellow cards in the space of a minute to also see red.